60-year-old patient, without considerable pre-existing conditions, with incidental a finding of a liver mass during ultrasound. CEUS shows an arterial inhomogeneous uptake of contrast agent (partially necrotic). In the venous portal phase beginning wash-out after 60 seconds, after 2 minutes and 3 minutes distinct wash out in late phase. Histological: cholangiocarcinoma (G3).

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